Photodynamic Therapy (PDT)

Photodynamic Therapy (PDT) is an advanced skin treatment that combines a photosensitizing agent with a specific wavelength of light to treat various skin conditions, including precancerous lesions like actinic keratosis, acne, and signs of photoaging. This non-invasive therapy offers effective results with minimal downtime, making it a popular choice for those seeking to improve their skin’s health and appearance.

How Photodynamic Therapy Works

PDT involves the application of a photosensitizing agent, such as Ameluz (Aminolevulinic acid 10%), to the skin. This compound is absorbed by abnormal or damaged skin cells. After an incubation period, during which the agent is absorbed, the treated area is exposed to a specific wavelength of light. The light activates the photosensitizing agent, leading to a reaction that destroys targeted cells and stimulates the skin’s natural healing processes.

Benefits of Photodynamic Therapy

  • Treatment of Precancerous Lesions: PDT is FDA-approved for treating actinic keratosis, a precancerous skin condition. The therapy effectively targets and eliminates abnormal cells, reducing the risk of progression to skin cancer.
  • Acne Reduction: PDT helps decrease acne by targeting overactive sebaceous glands, reducing oil production, and minimizing the bacteria that cause acne.
  • Skin Rejuvenation: Beyond treating medical conditions, PDT can improve the appearance of sun-damaged skin, reduce fine lines, and even out skin tone by addressing hyperpigmentation and textural irregularities.
  • Minimal Downtime: While some redness and peeling may occur post-treatment, PDT generally involves less downtime compared to more invasive procedures.

FDA Approval and Off-Label Uses

Ameluz is FDA-approved specifically for the treatment of actinic keratosis. However, its use in treating acne, reducing oiliness, and improving skin texture and smoothness is considered “off-label.” Dr. Yoo will discuss these uses during your consultation to ensure you are fully informed.

What to Expect During Your PDT Treatment

Consultation

During your consultation, Dr. Yoo will assess your skin and discuss your goals. She will determine the appropriate treatment plan, including the number of sessions needed to achieve the best results. Typically, 1-2 treatments are recommended for actinic keratosis, while 2-4 treatments may be needed for acne.

Procedure

On the day of your treatment, arrive with clean skin free of makeup, lotions, or creams. The photosensitizing agent will be applied to the treatment area and left to incubate for a specified period, allowing it to be absorbed by the target cells. After incubation, the area will be exposed to a specific light source to activate the agent, which typically takes 15-30 minutes.

Post-Treatment Care

After PDT, your skin will be extremely sensitive to light, and it is crucial to avoid any direct sunlight for at least 48 hours. Plan to stay indoors and cover windows to prevent exposure. You may experience redness, swelling, and a sunburn-like effect for a few days, followed by peeling or flaking of the skin. Dr. Yoo will provide you with specific post-care instructions to ensure a smooth recovery. Applying mineral sunscreen and wearing protective clothing when outdoors is essential during the healing process.

Results and Follow-Up

Results from PDT can vary based on the condition being treated. For actinic keratosis, the lesions should gradually fade as the skin heals. Acne reduction and skin rejuvenation benefits will become more apparent as the treatment course progresses. Dr. Yoo may recommend follow-up treatments or maintenance sessions to sustain your results.

FAQs About Photodynamic Therapy

Q: Is Photodynamic Therapy painful?
A: Some patients experience a tingling or burning sensation during the light exposure phase, but this typically subsides after the treatment. Dr. Yoo will ensure your comfort throughout the procedure.

Q: How many treatments will I need?
A: The number of treatments varies depending on the condition being treated. Typically, 1-2 sessions are sufficient for actinic keratosis, while acne may require 2-4 treatments.

Q: What should I avoid after treatment?
A: After PDT, it is crucial to avoid direct sunlight and even indirect light exposure for 48 hours. Dr. Yoo will provide detailed instructions on how to protect your skin during this sensitive period.

Q: Are there any side effects?
A: Common side effects include redness, swelling, peeling, and a sunburn-like effect, which usually resolve within a week. Dr. Yoo will provide aftercare guidance to help manage these symptoms.

Before and After Gallery

 

Explore the Benefits of Photodynamic Therapy

Photodynamic Therapy offers a powerful solution for treating precancerous skin lesions, acne, and signs of aging. With careful planning and expert guidance from Dr. Yoo, PDT can significantly improve the health and appearance of your skin. Schedule a consultation today to learn more about how PDT can help you achieve your skin goals.